With the Memorial Day weekend coming up, we've got one thing on our mind: vacation. If you haven't made plans, don't worry. We've mapped out nine of the best U.S. road trips to make that extra day off work count. From the picturesque plantations in Charleston, South Carolina, to surreal desert art installations in Marfa, Texas, these epic destinations are well worth the mileage. Roll down the windows, and turn up the music—we're going on a road trip.